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Special ISPNO Program
| Low grade glioma workshop | |
|---|---|
| 12:30 to 2:00 | Session 1: From lab discovery to clinical decision making |
| Moderator: Charles Eberhart Speakers: Cynthia Hawkins: BRAF FISH/ RT-PCR/ v600e - experience
with clinical testing & potential clinical/ diagnostic/ prognostic applications. Craig Horbinski: Clinical applications of BRAF alterations in PLGG. Keith Ligon: Update on genomics of non-BRAF low grade gliomas of other types and new genetic lesions emerging in this category of tumors and the use of multiplex technologies Sequenom, aCGH on FFPE in the clinical lab. |
|
| 2:00 to 3:00 | Session 2: Platforms for drug discovery in PLGG (cell lines, mouse models) |
| Moderator: Joshua Rubin Speakers: Xiao-Nan Li: Primary intracranial xenografts of low grade
astrocytomas. Nada Jabado: In vitro models of low grade astrocytomas. Stefan Pfister: In vivo BRAF models of disease. |
|
| 3:00 to 4:30 | Session 3: Current and novel drug therapies for PLGG. |
| Moderator: Darren Hargrave. Speakers: Olaf Witt: Update on SIOP trials for non-NF-1 LGG and
targeted therapies (SOLAR study) Jacques Grill:- Update on SIOP trials for NF-1 LGG and targeted therapies (VINILO study) Mark Kieran: Update on US trials and targeted therapies (BRAF/MEK inhibitor studies) |
|
| 4:30 to 5:00 | Workshop summary Future directions |